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 A Randomized, Prospective, Comparative Study about Effects and Safety of Sorafenib vs. Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma Patients with Portal Vein Tumor Thrombosis 相关领域
医学
肝细胞癌
内科学
索拉非尼
肝动脉灌注
胃肠病学
肿瘤科
肝癌
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作者：( Wang Yong Choi ) , ( Woo Jin Chung ) , ( Si Hyun Bae ) , ( Do Seon Song ).... 部分摘要：Aims: The treatment responses of advanced hepatocellular carcinoma( HCC) with portal vein tumor thrombosis(PVTT) were not acceptable and treatment modalities were limited. So, we compared effects and safety of sorafenib vs. hepatic arterial infusion chemotherapy( HAIC). Methods: We prospectively collected data of 58 advanced HCC with PVTT patients whose Child-Turcotte-Pugh(CTP) score range 5 to 7 in 6 university hospitals from January 2013 to Oct 2015. Each twenty nine patients were treated with sorafenib or HAIC. Results: 1. The mean age was 60.2±8.4 years old and 89.7% of the patients were male. Causes of HCC were HBV (67.3%), HCV (8.6%), alcohol (19.0%) and others (5.2%) |
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