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Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells
细胞外信号调节激酶1/细胞外信号调节激酶2丝裂原活化蛋白激酶信号传导和激活蛋白1和核因子kappaB转录因子的激活在单核细胞中尿酸单钠一水合物和焦磷酸钙晶体刺激的白细胞介素-8表达中起核心作用
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