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[高分] 学位论文 In Vitro Models for the Pancreatic Islet Using Dynamic Secretion Sensing and Mechanical Stimulation
利用动态分泌传感和机械刺激建立胰岛体外模型
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其它 | Diabetes, a disease of insulin insufficiency leading to improper glucose delivery to the cells of the body, affects millions worldwide with growing impact. For those most severely affected, an exogenous source of insulin is the only option to maintain glucose homeostasis. Islet transplantation is a recent therapy with the potential to offer insulin independence, but its widespread success is often limited by the availability of human, insulin-producing β cells whose quality has been adequately assessed prior to transplantation, a limitation of both cell source and method for assaying β cell function in a timely fashion. |
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