| 标题 |
 Treatment of refractory or relapsed myelodysplastic neoplasms with luspatercept: a multicenter Chinese study 利用增强现实对学龄前学生进行分形教学
相关领域
医学
内科学
胃肠病学
骨髓增生异常综合症
来那度胺
不利影响
血小板增多症
贫血
国际预后积分系统
输血
耐火材料（行星科学）
促红细胞生成素
血红蛋白
外科
骨髓
血小板
多发性骨髓瘤
物理
天体生物学
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| 网址 | |
| DOI | |
| 其它 |
Zhuxin Zhang # 1, Qinglin Hu # 1, Xudong Tang 2, Min Zhang 3, Jinsong Jia 4, Hongxia Shi 4, Xiaoqing Ding 5, Chen Yang 1, Miao Chen 1, Bing Han 6 Affiliations Expand PMID: 37682325 DOI: 10.1007/s00277-023-05334-y Abstract Few effective therapies are available to treat patients with relapsed/refractory myelodysplastic neoplasms (MDS). Luspatercept was shown to display good efficacy in a phase 3 clinical trial for lower-risk MDS (LR-MDS) patients, yet real-world data are limited, especially in China. Therefore, data from patients diagnosed as having MDS with low blasts and SF3B1 mutation (MDS-SF3B1) and MDS with SF3B1 mutation and thrombocytosis were retrospectively analyzed. Of the 23 enrolled patients, 17 (73.9%) were males (median age 67 years: range 29 to 80 years). Previously, a total of 22 (95.7%) patients had received recombinant human erythropoietin (rhEPO), 9 (39.1%) roxadustat, 7 (30.4%) lenalidomide and 3 (13.0%) hypomethylating agents (HMA). |
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