标题 |
Exploiting bacteria for cancer immunotherapy
利用细菌进行癌症免疫治疗
相关领域
免疫疗法
癌症
癌症免疫疗法
癌症治疗
肿瘤微环境
癌症治疗
生物
免疫学
医学
免疫系统
内科学
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题目:Exploiting bacteria for cancer immunotherapy DOI: 10.1038/s41571-024-00908-9 年份:2024 作者:Seong-Young Kwon, Hien Thi-Thu Ngo, Jinbae Son, Yeongjin Hong & Jung-Joon Min 摘要:Immunotherapy has revolutionized the treatment of cancer but continues to be constrained by limited response rates, acquired resistance, toxicities and high costs, which necessitates the development of new, innovative strategies. The discovery of a connection between the human microbiota and cancer dates back 4,000 years, when local infection was observed to result in tumour eradication in some individuals. However, the true oncological relevance of the intratumoural microbiota was not recognized until the turn of the twentieth century. The intratumoural microbiota can have pivotal roles in both the pathogenesis and treatment of cancer. |
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