| 标题 |
 Advances in Metabolic Engineering for the Accumulation of Astaxanthin Biosynthesis 虾青素生物合成积累的代谢工程研究进展
相关领域
虾青素
生物合成
代谢工程
生物化学
计算生物学
生物技术
化学
生物
酶
类胡萝卜素
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| 网址 | |
| DOI | |
| 其它 | 摘要：Astaxanthin, a lipophilic carotenoid renowned for its strong antioxidant activity, holds significant commercial value across industries such as feed, food, and cosmetics. Although astaxanthin can be synthesized through chemical methods, it may contain toxic by-products in the synthesized astaxanthin, limiting its application in medicine or functional food. Natural astaxanthin can be extracted from algae, however, the cultivation cycle of algae is relatively longer compared to microorganisms. With the advancement of synthetic biology and metabolic engineering, the method of microbial fermentation has emerged as a promising strategy for the large-scale production of astaxanthin. This article provides a comprehensive overview of the research progress in astaxanthin biosynthesis, highlighting the use of the natural host Xanthophyllomyces dendrorhous, and the heterologous hosts Yarrowia lipolytica and Saccharomyces cerevisiae. Additionally, future research prospects are also discussed. |
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