| 标题 |
 A multicenter, open, randomized controlled study for the efficacy and safty analysis of pegfilgrastim in preventing neutropenia in patients with non-small cell lung cancer after concurrent chemoradiotherapy 聚乙二醇格司汀预防非小细胞肺癌同期放化疗后中性粒细胞减少的多中心、开放、随机对照研究
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| 其它 | 发表时间2018年，作者ChiCTR，摘要：INTERVENTION: Experimental group :Subcutaneous injection of PEG‐rhG‐CSF 48 hours after the chemotherapy;Control group:Subcutaneous injection of rhG‐CSF when WBC or ANC during the chemotherapy; CONDITION: Non‐small cell lung cancer PRIMARY OUTCOME: Incidence of degree III/IV ANC reduction; SECONDARY OUTCOME: Incidence and duration of degree III/IV ANC reduction;Incidence and duration of FN; INCLUSION CRITERIA: (1) Aged 18 to 70 years old male and female; (2) Non‐small cell lung cancer patients diagnosed by histopathology or cytology; (3) Patients requiring multi‐cycle adjuvant chemotherapy; (4) Plan to accept a platinum‐containing two‐drug program; (5) KPS score = 70 points; (6) The estimated survival period is more than 3 months; (7) No obvious signs of hematological disease, Hb=7.5g/dL,WBC=3.010^9/L,ANC = 1.510^9/L, PLT = 8010^9/L. And no bleeding tendency; (8) No obvious abnormalities were observed in the electrocardiogram examination |
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