| 标题 |
[Molecular Mechanism of Action of hnRNP K and RTN3 in the Replication of Enterovirus 71]
[hnRNP K和RTN3在肠道病毒71复制中的分子作用机制]
相关领域
肠道病毒71
生物
核糖核酸
病毒学
病毒复制
微小病毒
翻译（生物学）
肠道病毒
病毒
基因
遗传学
信使核糖核酸
|
| 网址 |
求助人暂未提供
AI链接 nih.gov |
| DOI |
暂未提供，该求助的时间将会延长，查看原因？
|
| 其它 | Enterovirus 71 (EV71) is a neurotropic pathogen that can induce hand, foot and mouth disease in children. There is an appreciable mortality rate after EV71 infections. The mechanism of action of EV71 replication is not known. Recent work has identified some of cell factors of the host that participate in the synthesis of the RNA and proteins of EV71 (e.g., hnRNP K, reticulon 3 (RTN 3)). In that work, researchers used a competitive assay to show that hnRNP K can interact with EV71 5' UTR, which is required for efficient synthesis of viral RNA. Using a yeast two-hybrid system, other researchers demonstrated that RTN 3 interacts with the N-terminal domain of EV71 2C, which is crucial for replication of viral RNA. Here, we discuss recent work focusing on the molecular mechanisms of hnRNP K and RTN 3 in the synthesis of the RNA and proteins of EV71. |
| 求助人 | |
| 下载 | 暂无链接，等待应助者上传 |
|
温馨提示：该文献已被科研通 学术中心 收录，前往查看
科研通『学术中心』是文献索引库，收集文献的基本信息（如标题、摘要、期刊、作者、被引量等），不提供下载功能。如需下载文献全文，请通过文献求助获取。
|
乐乐乐乐乐乐
shinysparrow
嗯哼
带头大哥
大模型
xiaochou
Cz志生
穆紫
平常的过客
#include
minya
艾文
鬼见愁
脑洞疼
香蕉觅云
情怀
领导范儿
Diplogen
cc
银色的喵咪
皖公网安备34019202002308
