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Triple knockdown of CD11a , CD49d , and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity against solid tumors in mice
T细胞中CD11a、CD49d和PSGL1的三重敲除降低了CAR-T细胞毒性,但保留了抗小鼠实体瘤的活性
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期刊:Science Translational Medicine 作者:Hongye Wang; Zhaorong Wu; Dan Cui; Linke Bian; Zhigang Zheng; et al 出版日期:2025 |
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