| 标题 |
 Gene therapy for neovascular age-related macular degeneration by subretinal delivery of RGX-314: a phase 1/2a dose-escalation study 视网膜下注射RGX-314基因治疗新生血管性年龄相关性黄斑变性：一项1/2a期剂量递增研究
相关领域
黄斑变性
医学
脉络膜新生血管
眼科
肿瘤科
|
| 网址 | |
| DOI |
暂未提供，该求助的时间将会延长，查看原因？
|
| 其它 |
Summary Background Frequent anti-vascular endothelial growth factor A (VEGF-A) injections reduce the risk of rapid and severe vision loss in patients with neovascular age-related macular degeneration (nAMD); however, due to undertreatment, many patients lose vision over time. New treatments that provide sustained suppression of VEGF-A are needed. RGX-314 (currently known as ABBV-RGX-314) is an adeno-associated virus serotype 8 vector that expresses an anti-VEGF-A antigen-binding fragment, which provides potential for continuous VEGF-A suppression after a single subretinal injection. We report results on the safety and efficacy of subretinal injection of RGX-314 in patients with nAMD. |
| 求助人 | |
| 下载 | |
|
温馨提示：该文献已被科研通 学术中心 收录，前往查看
科研通『学术中心』是文献索引库，收集文献的基本信息（如标题、摘要、期刊、作者、被引量等），不提供下载功能。如需下载文献全文，请通过文献求助获取。
|
123
紫色水晶之恋
白桦
浦肯野
狼啸天
不懈奋进
苏卿
善良冷雁
杳鸢
哈哈哈哈
迟大猫
Archers
教生物的杨教授
114
大龙哥886
科目三
morena
夏筱
wadaxiwa
研友_菲
皖公网安备34019202002308
