The utility of ketoprofen for alleviating pain following dehorning in young dairy calves.

医学 酮洛芬 烧灼 利多卡因 麻醉 蠕动进给 局部麻醉剂 吗啡 外科 内科学 断奶 药理学
作者
Barry Milligan,T.F. Duffield,K. Lissemore
出处
期刊:Australian Veterinary Journal [Wiley]
卷期号:82 (9): 578-578 被引量:64
标识
DOI:10.1111/j.1751-0813.2004.tb11211.x
摘要

To determine if ketoprofen, in addition to local anaesthesia, reduces pain following dehorning, we experimentally dehorned dairy calves, less than 2 weeks of age, with (20 calves) or without (20 calves) intramuscular injections of ketoprofen. All calves received a local anesthetic (lidocaine) prior to dehorning and were dehorned with heat cauterization. Cortisol concentration was measured via jugular blood samples taken immediately before dehorning and at 3 and 6 hours following dehorning. Calf behavior was recorded between 0 and 2, 3 and 5, and 6 and 8 hours following dehorning. There was no significant (P > 0.10) effect on creep feed consumption, cortisol concentration, or any of the behavioral measures during the time periods studied. However, the difference in cortisol concentrations from the time of dehorning until 3 hours later was significantly lower (P < 0.05) in the ketoprofen-treated group. These results suggest that ketoprofen, in addition to local anesthesia, may alleviate short-term pain following dehorning with a butane dehorning device in dairy calves less than 2 weeks of age.
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