Intracranial Pressure and Cerebral Blood Flow Monitoring

Neurocritical care is dependent on the ability to accurately monitor cerebral physiology. One of the most important physiologic variables to consider is cerebral blood flow (CBF) because neuronal survival is directly linked to an appropriate match between metabolic demand and metabolic substrate. CBF depends on cerebral perfusion pressure (CPP), defined as the mean arterial blood pressure (mABP) minus the mean intracranial pressure (ICP).