酮替芬
医学
嗜酸性胃肠炎
嗜酸性粒细胞增多症
肠病
胃肠病学
食物过敏
十二指肠
内科学
免疫学
过敏
哮喘
疾病
作者
Junzo Suzuki,Yukihiko Kawasaki,Ruriko Nozawa,Masato Isome,Shigeo Suzuki,Ai Ishizawa,Hitoshi Suzuki
出处
期刊:PubMed
日期:2003-09-01
卷期号:21 (3): 193-7
被引量:47
摘要
We present a case report of a 10 years old boy with protein-losing enteropathy and eosinophilic gastroenteritis who had positive histamine release tests, increased allergen-specific IgE antibodies to some food items, and low levels of total serum protein and albumin. Upper gastrointestinal endoscopy revealed a number of polyps and diffuse gastritis. Biopsy specimens of the stomach and duodenum showed widespread eosinophilia and neutrophilia. Although a restricted diet was recommended, a diet which excluded foods with positive results to both histamine release test and allergen-specific IgE antibodies was poorly tolerated, and the patient rejected systemic administration of corticosteroids. Thus, we initiated an oral disodium cromoglycate (DSCG) and ketotifen therapy. After oral DSCG and ketotifen administration, the patient's condition improved gradually. Therefore, oral DSCG and ketotifen therapy might be considered as treatment option in patients with eosinophilic gastroenteritis and protein-losing enteropathy caused by food allergy.
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