医学
息肉切除术
粘膜切除术
荟萃分析
不利影响
科克伦图书馆
随机对照试验
结肠镜检查
大肠息肉
结直肠癌
外科
结直肠外科
梅德林
内科学
切除术
胃肠病学
癌症
腹部外科
政治学
法学
作者
Zheng Liang,Yongqiu Wei,Shu Tian Zhang,Peng Li
摘要
Abstract Background and Aim Neoplastic polyp removal is important for colorectal cancer prevention. Endoscopists have proposed cold snare endoscopic mucosal resection (CS‐EMR) as a solution to solve positive cutting edges and postoperative bleeding. However, many controversies regarding its specific performance in practice have been reported. The aim of this pooled analysis was to report the efficacy and safety of CS‐EMR. Methods PubMed/Medline, Embase, Google Scholar, and the Cochrane Library searched up to January 2022 to identify studies in which CS‐EMR was performed for the removal of colorectal polyps measuring less than 20 mm. The primary outcome was the complete resection rate (CRR), and the secondary outcome was the rate of adverse events. Results Eleven studies were included in the final analysis, which included 861 colorectal polyps. The overall CRR with CS‐EMR was 96.3% (95% CI, 93.9–98.2%). The early and delayed bleeding rates of CS‐EMR were 3.1% (95% CI, 1.2–5.5%) and 1.4% (95% CI, 0.6–2.4%), respectively. There were no statistical significances between CS‐EMR and cold snare polypectomy (CSP) in terms of the CRR and adverse events, as well as CS‐EMR and hot snare endoscopic mucosal resection (HS‐EMR). Conclusions For resecting colorectal polyps measuring ≤20 mm, CS‐EMR is an effective attempt. However, compared with CSP and HS‐EMR, CS‐EMR did not improve the efficiency and safety of polypectomy as expected. Multicenter randomized controlled trials are needed to compare CSP with CS‐EMR in the resection of <10 mm polyps and HSP with CS‐EMR in the resection of ≥10 mm polyps.
科研通智能强力驱动
Strongly Powered by AbleSci AI