Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis

Abstract From propolis of Lepidotrigona ventralis stingless bee collected in Tuyen Quang province, eight compounds were isolated and determined as lantanolic acid ( 1 ), moronic acid ( 2 ), (+)‐eudesmin (3) , (+)‐yangambin (4) , (+)‐syringaresinol (5) , (+)‐pinoresinol (6), dihydroconiferyl alcohol (7) and vanillin (8) using NMR and MS spectral data . Compounds 1 and 2 showed significant cytotoxicity against HepG‐2 cancer cell line with IC 50 values of 25.84±0.48 and 39.92±1.14 μg/mL, respectively.