Cu2+-doped zeolitic imidazolate frameworks and gold nanoparticle (AuNPs@ZIF-8/Cu) nanocomposites enable label-free and highly sensitive electrochemical detection of oral cancer-related biomarkers

Herein, we established a label-free, simple and sensitive electrochemical biosensor for oral cancer overexpressed 1 detection, which integrates Cu 2+ -doped ZIF-8 and AuNPs nanocomposites with a one-step strand displacement reaction.