A structure activity relationship study of 3,4′-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus
金黄色葡萄球菌
化学
微生物学
葡萄球菌
立体化学
细菌
生物
遗传学
作者
Alexander W. Weig,Patrick M. O'Conner,Jakub Kwieciński,Orry M. Marciano,Angelica Nunag,Andrew T. Gutierrez,Roberta J. Melander,Alexander R. Horswill,Christian Melander
Several analogues of the Staphylococcus aureus ArlRS inhibitor 3,4′-dimethoxyflavone were identified as more potent than the parent, in addition to one compound that suppresses oxacillin resistance in methicillin resistant S. aureus (MRSA).
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