New Frontiers in Phosphorothioate Formation: Harnessing Inorganic Phosphorus Sources

Organic phosphorothioates are a class of organic compounds containing the C-S-P structural motif, known for their unique physical and chemical properties. These compounds hold significant value in various fields, including agriculture, pharmaceuticals, and materials science, particularly playing a crucial role in agrochemicals and nucleotide modification. Traditionally, phosphorothioates have been synthesized primarily through the formation of P-S bonds or direct phosphorothioation reactions from organic phosphorus sources such as P(O)H and P(O)SH. In recent years, new strategies utilizing inorganic phosphorus sources, such as P