亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Exploring the effect of gestational diabetes mellitus on retinal vascular morphology by PKSEA-Net

妊娠期糖尿病 糖尿病 视网膜 医学 内科学 怀孕 眼科 妊娠期 内分泌学 生物 遗传学
作者
Li-Gang Jiang,Yimei Ji,Mengting Liu,Ruogu Fang,Zhentao Zhu,Meizhen Zhang,Yuhua Tong
出处
期刊:Frontiers in Cell and Developmental Biology [Frontiers Media]
卷期号:12
标识
DOI:10.3389/fcell.2024.1532939
摘要

Background Gestational diabetes mellitus (GDM) is a temporary metabolic disorder in which small retinal vessels may have experience subtle changes before clinical lesions of the fundus retina appear. An innovative artificial intelligence image processing technology was applied to locate and analyze the small retinal vessel morphology and accurately evaluate the changes of the small retinal vessels in GDM patients and pregnant women with normal blood glucose and non-pregnant women with normal blood glucose. Methods The subjects were divided into three groups:GDM group, pregnant control group (PC), and normal control group (NC). Use optical coherence tomography angiography (OCTA) to collect OCT images of subjects,and perform quantitative identification and analysis of retinal vessel parameters based on artificial intelligence measurement software integrated the prior knowledge supervised edge-aware multi-task network (PKSEA-Net): Retinal arteriolar lumen diameter (RALD), retinal arteriolar outer diameter (RAOD), retinal venular lumen diameter (RVLD),retinal venular outer diameter (RVOD),arterial wall thickness (AWT),venular wall thickness (VWT),arterial wall to lumen ratio (AWLR),venular wall to lumen ratio (VWLR),arterial wall cross-sectional area (AWCSA),venular wall cross-sectional area (VWCSA), arteriovenous ratio (AVR). Results This study revealed significant differences in RVOD, RVLD, VWT, VWCSA and AVR between the GDM group and the PC group ( p = 0.005, p < 0.027, p = 0.008, p = 0.001, p = 0.022), significant differences in RVOD, RVLD, VWT, VWCSA and AVR between the GDM group and the NC group ( p < 0.001, p = 0.001, p < 0.001, p < 0.001, p = 0.001). In GDM group, RVOD, RVLD, VWT and VWCSA increased, while AVR decreased. There were no significant differences in RVOD, RVLD, VWT, VWCSA and AVR between PC group and NC group ( p = 0.139, p = 0.263, p = 0.107, p = 0.059, p = 0.218), and no significant differences in VWLR among the three groups ( p > 0.05). No significant difference was observed in retinal artery vascular parameters (RAOD, RALD, AWT, AWLR, AWCSA) across the three groups ( p > 0.05). Conclusion There were increases in RVOD, RVLD, VWT, and VWCSA, decrease in AVR in patients with GDM. However, no significant difference of retinal vascular parameters was shown between normal pregnant women and normal non-pregnant women. PKSEA-Net can assist to identify changes in retinal vascular morphology and diagnose micro-vascular lesion early in normal pregnant women and high-risk groups of GDM.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
米奇妙妙屋完成签到,获得积分10
33秒前
tylscxf完成签到,获得积分10
33秒前
YifanWang完成签到,获得积分0
35秒前
量子星尘发布了新的文献求助30
42秒前
56秒前
启震发布了新的文献求助10
57秒前
1分钟前
1分钟前
1分钟前
1分钟前
www完成签到,获得积分20
1分钟前
1分钟前
风车术完成签到,获得积分20
1分钟前
1分钟前
风车术发布了新的文献求助10
1分钟前
shinian发布了新的文献求助10
1分钟前
1分钟前
小岩完成签到 ,获得积分10
1分钟前
wanci应助风车术采纳,获得10
1分钟前
2分钟前
为神指路发布了新的文献求助30
2分钟前
2分钟前
2分钟前
为神指路完成签到,获得积分20
2分钟前
2分钟前
2分钟前
33完成签到,获得积分0
2分钟前
共享精神应助科研通管家采纳,获得20
2分钟前
量子星尘发布了新的文献求助10
2分钟前
行走完成签到,获得积分10
3分钟前
3分钟前
3分钟前
姚老表完成签到,获得积分10
3分钟前
mashibeo完成签到,获得积分10
3分钟前
4分钟前
量子星尘发布了新的文献求助10
4分钟前
脑洞疼应助zhiweiyan采纳,获得10
4分钟前
4分钟前
安渝完成签到 ,获得积分10
4分钟前
孙孙应助hky采纳,获得20
4分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976649
求助须知:如何正确求助?哪些是违规求助? 3520756
关于积分的说明 11204729
捐赠科研通 3257502
什么是DOI,文献DOI怎么找? 1798733
邀请新用户注册赠送积分活动 877897
科研通“疑难数据库(出版商)”最低求助积分说明 806629