Recent advances in 2D metal carbides and nitrides (MXenes): synthesis and biological application

As a new two-dimensional (2D) material, transition metal carbides and nitrides (MXenes) have attracted much attention because of their excellent physical and chemical properties. In recent years, MXenes have been widely applied in the biological field due to their high biocompatibility, abundant surface groups, good conductivity, and photothermal properties. Here, the main synthesis methods of MXenes and the analysis of the advantages and disadvantages of each method are presented in detail. Then, the latest developments of MXenes in the biological field, including biosensing, antibacterial activity, reactive oxygen species (ROS) and free radical scavenging, tissue repair and antitumor therapy are comprehensively reviewed. Finally, the current challenges and future development trends of MXenes in biological applications are discussed.