化学
天然产物
生物合成
质谱法
产品(数学)
色谱法
生物化学
酶
几何学
数学
作者
Hai Anh Vu,Moonyoung Kang,Jens Wurlitzer,Sarah Heinicke,Chenxin Li,Joshua C. Wood,Veit Grabe,C. Robin Buell,Lorenzo Caputi,Sarah E. O’Connor
摘要
Plants produce an extraordinary array of natural products (specialized metabolites). Notably, these structurally complex molecules are not evenly distributed throughout plant tissues but are instead synthesized and stored in specific cell types. Elucidating both the biosynthesis and function of natural products would be greatly facilitated by tracking the location of these metabolites at the cell-level resolution. However, detection, identification, and quantification of metabolites in single cells, particularly from plants, have remained challenging. Here, we show that we can definitively identify and quantify the concentrations of 16 molecules from four classes of natural products in individual cells of leaf, root, and petal of the medicinal plant
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