Evaluation of Carbon Fiber and Titanium Surgical Implants for Proton and Photon Therapy

医学 质子疗法 质子 放射治疗 外科 材料科学 冶金 量子力学 物理
作者
Nicolas Depauw,J. Pursley,Santiago A. Lozano‐Calderón,Chirayu G. Patel
出处
期刊:Practical radiation oncology [Elsevier BV]
卷期号:13 (3): 256-262 被引量:6
标识
DOI:10.1016/j.prro.2023.01.009
摘要

Impending and actual pathologic fractures secondary to metastatic bone disease, lymphoma, or multiple myeloma often require intramedullary fixation followed by radiation therapy. Because of carbon's low atomic number, there are reduced computed tomography (CT) imaging artifacts and dose perturbation when planning postoperative radiation for carbon fiber (CF) rods. Herein, we characterize the dosimetric properties of CF implants compared with titanium alloy (TA) for proton and photon.TA and CF samples were acquired from an implant manufacturer. Material characteristics were evaluated by CT scans with and without metal artifact reduction (MAR). Relative stopping power (RSP) was determined from the range pull-back of each sample in a 20-cm range proton beam. Photon transmission measurements were made in a solid water phantom and compared with the modeled dosimetry from the RayStation planning system.CF caused no visible CT artifacts, and MAR was not necessary for Hounsfield unit (HU) determination (median, 364 HU) or contouring, whereas TA (median, 3071 HU) caused substantial artifacts, which were improved, but not eliminated by MAR. The proton RSP was measured as 3.204 for TA and 1.414 for CF. For 6 MV photons, the measured transmission was 89.3% for TA and 98% for CF. CF RSP calculation and transmission from CT HU showed a physical density overestimate compared with measurements, which would cause a slight, but acceptable, dose uncertainty (<10% proton range or 1% photon transmission).With a density similar to bone, CF implants did not cause imaging artifacts and minimal dose perturbation compared with TA. Although the CF proton RSP is underestimated and the photon attenuation is overestimated by the HU, both effects are relatively small and may be most easily accounted for by planning with a 2-mm expansion around organs at risk beyond or in close proximity to the implant.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
完美世界应助金鑫水淼采纳,获得10
1秒前
小周完成签到,获得积分20
1秒前
2秒前
陈文青发布了新的文献求助10
2秒前
赘婿应助滑稽剑客采纳,获得10
3秒前
量子星尘发布了新的文献求助10
3秒前
3秒前
搜集达人应助Laospakalfski采纳,获得10
3秒前
xy完成签到,获得积分10
5秒前
5秒前
heylay完成签到 ,获得积分10
6秒前
wangrswjx发布了新的文献求助10
6秒前
8秒前
8秒前
流沙完成签到,获得积分10
8秒前
10秒前
汉堡包应助与山采纳,获得10
10秒前
Jasper应助流沙采纳,获得10
12秒前
华桦子完成签到 ,获得积分10
13秒前
zland完成签到,获得积分10
14秒前
爆米花应助行兹在兹采纳,获得10
14秒前
14秒前
15秒前
盲点花生发布了新的文献求助10
16秒前
17秒前
万能图书馆应助陈文青采纳,获得10
18秒前
笨鸟先飞发布了新的文献求助10
18秒前
19秒前
英姑应助zland采纳,获得10
19秒前
20秒前
天真的迎天完成签到,获得积分10
21秒前
21秒前
max完成签到,获得积分10
22秒前
wangrswjx完成签到,获得积分10
23秒前
张易完成签到,获得积分10
23秒前
丘比特应助Hony132采纳,获得30
23秒前
解语花举报孤独寻云求助涉嫌违规
24秒前
可可完成签到 ,获得积分10
25秒前
26秒前
哥哥发布了新的文献求助10
28秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3971644
求助须知:如何正确求助?哪些是违规求助? 3516269
关于积分的说明 11181862
捐赠科研通 3251441
什么是DOI,文献DOI怎么找? 1795889
邀请新用户注册赠送积分活动 876131
科研通“疑难数据库(出版商)”最低求助积分说明 805246