[Pay attention to the clinical application of radiofrequency ablation in the treatment of neuropathic pain].

Neuropathic pain is the pain triggered or caused by primary damage and dysfunction of the nervous system. Its pathogenesis is complex, involving changes in ion channel function, abnormal action potential generation and expansion, and central and peripheral sensitization. Therefore, it has always been the most intractable problem in clinical pain diagnosis and treatment, and there are many kinds of treatment methods. In addition to various oral drugs, nerve block, pulsed radiofrequency, radiofrequency ablation, central nerve electrical stimulation, peripheral nerve electrical stimulation, intra-thecal infusion system, craniotomy nerve decompression or carding, the dorsal root entry zone disfigurement, etc. various methods have mixed efficacy. So far, radiofrequency ablation of peripheral nerves is still the most simple and effective means for the treatment of neuropathic pain. In this paper, the definition, clinical manifestations, pathological mechanism and the treatment methods of radiofrequency ablation of neuropathic pain were expounded, in order to provide reference for related clinicians in radiofrequency ablation.神经病理性疼痛是神经系统原发性损害和功能障碍所激发或引起的疼痛。其发病机制复杂，牵涉到离子通道功能改变、异常动作电位的产生与扩布以及中枢和外周敏化，因而一直是临床疼痛诊疗中最棘手的问题，治疗方法也种类繁复。除各种口服药物外，神经阻滞、脉冲射频、射频消融、中枢神经电刺激、外周神经电刺激、鞘内输注系统、开颅手术神经减压或梳理、脊神经根入髓区毁损术等不一而足，各种方法的疗效也褒贬不一。针对周围神经的射频消融仍然是治疗神经病理性疼痛最简捷有效的手段。本文从神经病理性疼痛的定义、临床表现、病理机制以及射频消融的治疗方法等几个方面分别进行了阐述，以期为相关临床医师进行射频消融治疗提供参考。.