Phase I or II Study of Ribociclib in Combination With Topotecan-Temozolomide or Everolimus in Children With Advanced Malignancies: Arms A and B of the AcSé-ESMART Trial
医学
依维莫司
拓扑替康
替莫唑胺
肿瘤科
内科学
儿科
作者
Francisco Bautista,Xavier Paoletti,Jonathan Rubino,Caroline Brard,Keyvan Rezai,Souad Nebchi,Nicolas André,Isabelle Aerts,Emilie De Carli,Natasha K. A. van Eijkelenburg,Estelle Thebaud,Nadège Corradini,Anne-Sophie Defachelles,Stéphane Ducassou,Raphael J. Morscher,Gilles Vassal,Birgit Geoerger
PURPOSEAcSe-ESMART is a proof-of-concept, phase I or II, platform trial, designed to explore targeted agents in a molecularly enriched cancer population. Arms A and B aimed to define the recommende...