Nitrate‐Free Synthesis and Electrospinning of Carbonated Hydroxyapatite Coatings on TA6V Implants

Abstract TA6V (Ti‐6Al‐4V) titanium alloy is commonly used in implantology due to its biocompatibility and interesting mechanical properties. However, its lack of bioactivity is responsible for orthopedic implants loosening, eventually leading to the necessity for a revision surgery. In this study, inorganic coatings are developed with the aim of improving osteo‐integration of TA6V implants. To this end, a carbonated calcium phosphate apatite, already reported to be osteo‐conductive and naturally present in bone tissue, is shaped in the form of micro‐sized filaments, via the electrospinning process, in order to mimic the architecture of the collagen fibrils naturally present in the bone extracellular matrix. The process is then adapted to coat complex, 3D implants. Cellular assays with MG‐63 highlight that cell viability and proliferation are promoted on the coated implant, as a result of both its chemical and morphological properties.