清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Analysis of Multi-Part Phenotypic Changes in Skin to Characterize the Trajectory of Skin Aging in Chinese Women

皱纹 皮肤老化 表型 健康衰老 医学 皮肤病科 生物 老年学 遗传学 基因
作者
Yan Zhang,Xiaoyu Liu,Jingpu Wang,Lê Thi Huong Dû,Yanyun Ma,Wei Liu,Rui Ye,Yali Yang,Hui Xu
出处
期刊:Clinical, Cosmetic and Investigational Dermatology [Dove Medical Press]
卷期号:Volume 15: 631-642 被引量:7
标识
DOI:10.2147/ccid.s349401
摘要

As the human body's largest organ exposed to the external environment, the skin suffers from internal and external aging factors, leading to wrinkles, loss of elasticity, sagging, and rough appearance. However, little is known of the characteristics of skin aging of different body parts in Chinese women. Here, we study the signs of extrinsic skin aging in different body parts to identify the knowledge map of manifestations of aging in Chinese women.Wrinkle and texture phenotypes and collagen samples from the face, neck, hands, and arms of 326 Chinese women were collected. The correlations between phenotypes and ages and the differences in phenotypes by age were evaluated.The wrinkle and texture phenotypes around the eyes and mouth and of the hands were strongly correlated with age. Ages 32 and 58 showed the largest number of differentially changed aging phenotypes. The number of aging phenotypes increased sharply between the ages of 24 and 30, suggesting that the skin was undergoing rapid aging. Eye aging was the most rapidly changing phenotype between 19 and 30 years old. Wrinkles at the corner of the eyes showed a significant difference in the older group, suggesting an early onset and long-term effects.This is the first study to be performed on the characteristics of skin aging among Chinese women that takes account of multiple areas of the body. It was found that 24 years old was the time point at which the skin begins to age in Chinese women. This provides important clues for aging-related research and personalized skin care.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
心想柿橙发布了新的文献求助10
2秒前
量子星尘发布了新的文献求助10
33秒前
跳跃的鹏飞完成签到 ,获得积分10
40秒前
心想柿橙完成签到,获得积分10
41秒前
科研通AI2S应助风中不斜采纳,获得10
42秒前
婼汐完成签到 ,获得积分10
1分钟前
1分钟前
甜蜜发带完成签到 ,获得积分0
1分钟前
1分钟前
量子星尘发布了新的文献求助10
1分钟前
简因完成签到 ,获得积分10
2分钟前
3分钟前
Becky完成签到 ,获得积分10
3分钟前
量子星尘发布了新的文献求助10
3分钟前
桥西小河完成签到 ,获得积分10
3分钟前
胡可完成签到 ,获得积分10
3分钟前
3分钟前
3分钟前
4分钟前
量子星尘发布了新的文献求助10
4分钟前
4分钟前
紫熊完成签到,获得积分10
4分钟前
5分钟前
111完成签到 ,获得积分10
5分钟前
量子星尘发布了新的文献求助10
5分钟前
矢思然完成签到,获得积分10
5分钟前
6分钟前
量子星尘发布了新的文献求助10
6分钟前
7分钟前
小二郎应助科研通管家采纳,获得10
7分钟前
8分钟前
小花匠发布了新的文献求助50
8分钟前
呃呃呃呃呃完成签到 ,获得积分10
8分钟前
冷傲半邪完成签到,获得积分10
8分钟前
量子星尘发布了新的文献求助10
8分钟前
8分钟前
9分钟前
紫熊发布了新的文献求助10
9分钟前
张同学快去做实验呀完成签到,获得积分10
9分钟前
10分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Social Research Methods (4th Edition) by Maggie Walter (2019) 2390
A new approach to the extrapolation of accelerated life test data 1000
北师大毕业论文 基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 390
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 360
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4008397
求助须知:如何正确求助?哪些是违规求助? 3548131
关于积分的说明 11298711
捐赠科研通 3282900
什么是DOI,文献DOI怎么找? 1810274
邀请新用户注册赠送积分活动 885975
科研通“疑难数据库(出版商)”最低求助积分说明 811209