介电泳
检出限
电容
电容感应
细菌
材料科学
纳米技术
计算机科学
化学
生物
色谱法
微流控
电极
物理化学
遗传学
操作系统
作者
Yanting Jiang,Jayne Wu,Shigetoshi Eda
标识
DOI:10.1109/hi-poct54491.2022.9744059
摘要
Sensitive and specific detection of pathogenic bacteria was important for early and appropriate antibiotic treatment of infected humans and animals. Also, the detection of Gram-negative bacteria, such as Escherichia, had a significant implication in food safety as the organisms were a major cause of food-borne illnesses. Our previous studies demonstrated that dielectrophoretic (DEP) capacitive sensing could be used to accelerate the detection by simultaneous DEP attraction of target bioparticles to the sensor surface and direct monitoring of interfacial capacitance. In this report, we implemented stepwise voltages for the detection of Gram-negative bacteria with high sensitivity and selectivity. The sensor achieved a detection limit of 282.1 cells/mL and a dynamic range of 282.1~2.82×10 4 cells/mL. The tunable dielectrophoresis approach is applicable for improved detection of other bioparticles.
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