清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Day 2 neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios for prediction of delayed cerebral ischemia in subarachnoid hemorrhage

医学 蛛网膜下腔出血 淋巴细胞 内科学 逻辑回归 中性粒细胞与淋巴细胞比率 缺血 入射(几何) 队列 回顾性队列研究 胃肠病学 光学 物理
作者
W. R. Bolton,Parjeet Kaur Gharial,Christopher Yusuf Akhunbay-Fudge,Paul Chumas,Ryan Mathew,Ian Anderson
出处
期刊:Neurosurgical Focus [Journal of Neurosurgery Publishing Group]
卷期号:52 (3): E4-E4 被引量:11
标识
DOI:10.3171/2021.12.focus21642
摘要

Recent evidence has suggested that an admission neutrophil-to-lymphocyte ratio (NLR) of ≥ 5.9 predicts delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH). The primary aims of this study were to assess reproducibility and to ascertain the predictive ability of NLR on subsequent days postictus. Secondary aims included identification of additional inflammatory markers.A single-center, retrospective study of all patients aged ≥ 18 years with aSAH between May 2014 and July 2018 was performed. Patient characteristics, DCI incidence, operative features, and outcomes (on discharge and at 3 months postictus) were recorded. C-reactive protein (CRP) and full blood count differentials were recorded on admission and through day 8 postictus or at discharge. In total, 403 patients were included in the final analysis.Ninety-six patients (23.8%) developed DCI with a median time from ictus of 6 days (IQR 3.25-8 days). A platelet-to-lymphocyte ratio (PLR) cutoff ≥ 157 and CRP cutoff ≥ 27 was used in our cohort. In a multiple binary logistic regression model, after controlling for known DCI predictors, day 2 NLR ≥ 5.9 (OR 2.194, 95% CI 1.099-4.372; p = 0.026), day 1 PLR ≥ 157 (OR 2.398, 95% CI 1.1072-5.361; p = 0.033), day 2 PLR ≥ 157 (OR 2.676, 95% CI 1.344-5.329; p = 0.005), and CRP ≥ 27 on days 3, 4, and 5 were predictive of DCI.The results of this study have confirmed the association between NLR and DCI and have demonstrated the predictive potential of PLR and CRP, suggesting that NLR and PLR at day 2, and CRP from day 3 onward, may be better predictors of DCI than those measurements at the time of ictus.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
7秒前
14秒前
科研通AI2S应助liudy采纳,获得10
15秒前
26秒前
QiaoHL完成签到 ,获得积分10
26秒前
37秒前
50秒前
1分钟前
1分钟前
1分钟前
十二完成签到 ,获得积分10
1分钟前
2分钟前
Airi发布了新的文献求助10
2分钟前
2分钟前
2分钟前
2分钟前
2分钟前
Ava应助Airi采纳,获得10
2分钟前
Tiger发布了新的文献求助10
2分钟前
Tiger完成签到,获得积分10
3分钟前
3分钟前
imi完成签到 ,获得积分10
3分钟前
3分钟前
3分钟前
3分钟前
4分钟前
4分钟前
Raunio完成签到,获得积分10
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
4分钟前
得咎发布了新的文献求助10
4分钟前
5分钟前
高分求助中
The Oxford Handbook of Social Cognition (Second Edition, 2024) 1050
Kinetics of the Esterification Between 2-[(4-hydroxybutoxy)carbonyl] Benzoic Acid with 1,4-Butanediol: Tetrabutyl Orthotitanate as Catalyst 1000
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
Handbook of Qualitative Cross-Cultural Research Methods 600
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3139610
求助须知:如何正确求助?哪些是违规求助? 2790479
关于积分的说明 7795355
捐赠科研通 2446958
什么是DOI,文献DOI怎么找? 1301526
科研通“疑难数据库(出版商)”最低求助积分说明 626259
版权声明 601176