3D生物打印
纳米技术
组织工程
生物相容性
材料科学
3D打印
细胞功能
计算机科学
生物医学工程
细胞
工程类
复合材料
化学
生物化学
冶金
作者
Soroosh Derakhshanfar,Rene Mbeleck,Kaige Xu,Xingying Zhang,Wen Zhong,Malcolm Xing
标识
DOI:10.1016/j.bioactmat.2017.11.008
摘要
3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequisite toward advancing 3D printing applications in tissue engineering. Printability to improve fabrication process and cell encapsulation are two of the main factors to be considered in development of 3D bioprinting. Other important factors include but are not limited to printing fidelity, stability, crosslinking time, biocompatibility, cell encapsulation and proliferation, shear-thinning properties, and mechanical properties such as mechanical strength and elasticity. In this review, we recite recent promising advances in bioink development as well as bioprinting methods. Also, an effort has been made to include studies with diverse types of crosslinking methods such as photo, chemical and ultraviolet (UV). We also propose the challenges and future outlook of 3D bioprinting application in medical sciences and discuss the high performance bioinks.
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