苯硼酸
催化作用
可重用性
苯并咪唑
产量(工程)
化学
金属有机骨架
反应条件
组合化学
偶联反应
核化学
有机化学
材料科学
计算机科学
冶金
吸附
程序设计语言
软件
作者
Nagaraj Anbu,Amarajothi Dhakshinamoorthy
标识
DOI:10.1016/j.jiec.2018.04.020
摘要
The present work reports the catalytic activity of Cu3(BTC)2 (BTC: 1,3,5-benzenetricarboxylate) in C–N coupling of benzimidazole with phenylboronic acid to afford N-arylbenzimidazole in high yield under mild reaction conditions. A series of optimization results indicate that Et3N is an optimal base to promote this reaction. This protocol is applied to synthesize a series of N-arylated azoles in moderate to high yields under the present experimental conditions. Furthermore, the catalyst stability is checked by powder XRD, UV–vis diffuse reflectance spectroscopy and FT-IR. These data indicate that there is a change in the crystalline nature of Cu3(BTC)2 after the reaction, but however, reusability studies reveal that the catalyst can be recycled four cycles without any decay in its activity.
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