电离辐射
胸腺细胞
程序性细胞死亡
辐照
生物
核医学
男科
分子生物学
化学
免疫学
医学
细胞凋亡
生物化学
T细胞
物理
核物理学
免疫系统
作者
Sharetskiĭ An,Kulish IuS,Abramova Mr
出处
期刊:PubMed
日期:2000-04-25
卷期号:40 (1): 71-5
摘要
The cortical thymocytes of rats in whole organism, isolated lobes of thymus and cells suspension were exposed to ionizing radiation in a wide range of doses (0.1-200 cGy). In contrast to relatively high dose radiation (50-200 cGy), exposure to doses of 10 cGy resulted in cell death without DNA degradation. The level of doses lower than 10 cGy (0.5-5 cGy) induced thymocyte death which is independent of DNA degradation, RNA and protein synthesis. With decrease in radiation dose, the increase of latent period preceding cell death took place.
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