表面改性
纳米技术
纳米颗粒
材料科学
纳米医学
生物相容性
涂层
生物分子
聚合物
药物输送
磁性纳米粒子
化学工程
接触角
粘附
工程类
复合材料
冶金
作者
Rahul Maheshwari,Nidhi Raval,Rakesh K. Tekade
出处
期刊:Methods in molecular biology
日期:2019-01-01
卷期号:: 191-201
被引量:12
标识
DOI:10.1007/978-1-4939-9516-5_13
摘要
Colloidal nanoparticles offering multiple biological applications carry tremendous potential to be developed as future medicines or nanomedicines. However, to decrease the particle agglomeration and enhance the stability of nanoparticles, functionalization could be of great interest. Functionalization is also capable of molding the delivery system for targeting and selective delivery of drugs and other biomolecules. In particular, the control over the size and the surface chemistry is crucial, since the successful applications in the prevention of diseases required biocompatibility at biological interfaces. Regardless of the advancements noted in nanotechnology-based nanoparticles, the development of nontoxic/biocompatible multi-functionalized nanoparticles is still a critical problem for researchers and requires urgent attention. In this chapter, an overview of nanoparticle functionalization with particular emphasis on its principle, needs, and formulation strategies has been discussed. Moreover, various applications of different surface-functionalized nanoparticles such as gold, silver, silicon, magnetic, liposomes, dendrimers, poly-lactic-co-glycolic acid, and solid lipid nanoparticles have also been presented.
科研通智能强力驱动
Strongly Powered by AbleSci AI