Wnt信号通路
头发周期
信号转导
毛囊
细胞生物学
生物
作者
Anastasia P. Nesterova,Anton Yuryev
出处
期刊:InTech eBooks
[InTech]
日期:2017-05-03
被引量:1
摘要
Signaling pathways that control coordination of hair follicle cells genetic program are the convenient model for explaining the hierarchy of intercellular interactions governing cyclic growth of hair. This chapter describes models of molecular signaling pathways specific to dermal papilla cells from balding human scalp in hair follicle cycle. These models include already published data, as well as information inferred from pathway analysis of microarray data and protein-protein interaction database. Interplay of androgenic-alopecia-related signaling pathways FGF, TGFB, BMP, and WNT, as well as cyclin-dependent kinases signaling, is shown.
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