快速眼动睡眠行为障碍
多导睡眠图
荟萃分析
睡眠(系统调用)
医学
阻塞性睡眠呼吸暂停
呼吸不足
睡眠呼吸暂停
睡眠开始
内科学
听力学
呼吸暂停
精神科
失眠症
计算机科学
操作系统
作者
Ye Zhang,Rong Ren,Linghui Yang,Larry D. Sanford,Xiangdong Tang
标识
DOI:10.1016/j.smrv.2020.101362
摘要
Polysomnographic studies conducted to explore sleep changes in idiopathic rapid eye movement sleep behavior disorder (iRBD) have not established clear relationships between sleep disturbances and iRBD. To explore the polysomnographic differences between iRBD patients and healthy controls and their associated factors, an electronic literature search was conducted in EMBASE, MEDLINE, All EBM databases, CINAHL, and PsycINFO inception to December 2019.34 studies were identified for systematic review, 33 of which were used for meta-analysis. Meta-analyses revealed significant reductions in total sleep time (SMD = -0.212, 95%CI: −0.378 to −0.046), sleep efficiency (SMD = -0.194, 95%CI: −0.369 to −0.018), apnea hypopnea index (SMD = -0.440, 95%CI: −0.780 to −0.101), and increases in sleep latency (SMD = 0.340, 95%CI: 0.074 to 0.606), and slow wave sleep (SMD = 0.294, 95%CI: 0.064 to 0.523) in iRBD patients compared with controls. Furthermore, electroencephalogram frequency components during REM sleep were altered in iRBD patients compared with controls; however, the specific changes could not be determined. Our findings suggest that polysomnographic sleep is abnormal in iRBD patients. Further studies are needed on underlying mechanisms and associations with neurodegenerative diseases.
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