龙葵
蜜环菊
化学
一氧化氮
体外
乙醇
消炎药
IC50型
传统医学
立体化学
植物
生物化学
有机化学
生物
药理学
医学
作者
Yan Liu,Xin Yin,Yanping Sun,Yuan Liu,Yuanyuan Zhou,Juan Pan,Wei Guan,Bing‐You Yang,Hai‐Xue Kuang
标识
DOI:10.1080/14786419.2020.1815740
摘要
Three new compounds (1-3), were isolated from the ethanol extract of the roots of Solanum melongena L., together with twenty-seven knowns (4-30). On basis of their 1 D and 2 D NMR data, the chemical structures of islated compounds were elucidated combined with HR-MS and the relative values in literatures. In addition, the isolations were evaluated for the potential anti-inflammatory activity, by virtue of RAW 264.7 cells model induced by lipopolysaccharide (LPS)in vitro inhibitory activities on nitric oxide (NO) production. Compounds 12 and 21 showed moderate inhibition of NO production with IC50 values of 32.8 and 20.2 μM, respectively.
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