生物
功能(生物学)
癌症
硒
人类健康
医学
计算生物学
平衡
生物信息学
遗传学
细胞生物学
化学
环境卫生
有机化学
作者
Cindy D. Davis,Petra A. Tsuji,John A. Milner
标识
DOI:10.1146/annurev-nutr-071811-150740
摘要
The discovery of multiple selenoproteins has raised tantalizing questions about their role in maintaining normal cellular function. Unfortunately, many of these remain inadequately investigated. While they have a role in maintaining redox balance, other functions are becoming increasingly recognized. As the roles of these selenoproteins are further characterized, a better understanding of the true physiological significance of this trace element will arise. This knowledge will be essential in defining optimum intakes to achieve cellular homeostasis in order to optimize health, including a reduction in cancer, for diverse populations. Human variation in the response to selenium likely reflects significant interactions between the type and amounts of selenium consumed with the genome and a host of environmental factors including the totality of the diet, as discussed in this review.
科研通智能强力驱动
Strongly Powered by AbleSci AI