SYNTHESIS AND CHARACTERIZATION OF A CARBOXYLIC ACID DERIVATIVE FOR LIPOSOMAL PREPARATIONS

A new compound with cholesteryl-derived structure containing a carboxylic acid functional group has been prepared in four steps starting from cholesterol. The product has been characterized by 1 H, 13 C NMR and mass spectrometry analysis. It will be used for liposomal preparations, in order to evaluate the interaction of liposomes functionalized with carboxylic acid functional groups and hydroxyapatite. Rezumat