黄原酮
夜蛾科
金丝桃属
化学
细胞毒性
立体化学
间苯三酚
酚类
量子化学
有机化学
体外
分子
植物
生物
生物化学
作者
Jiaqi Zhao,Feng Wei,Honglin Liu,Rui Qin,Xinzhou Yang
标识
DOI:10.1080/14786419.2022.2156999
摘要
Three previously undescribed compounds including two aromatic acid derivatives (1–2), and one xanthone (3), together with ten known compounds (4–13) were isolated from the aerial part of Hypericum hengshanense. The planar structures of three new compounds were established by 1 D and 2 D NMR and MS data. And the absolute configurations of compounds 1–2 were determined by the quantum chemical ECD calculations. Compounds 1–2 showed weak cytotoxicity against Hep-2 human cancer cell lines with IC50 values of 65.1 ± 2.7 and 78.0 ± 1.0 μg/mL, respectively.
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