Comparison of pure laparoscopic donor right posterior sectionectomy versus right hemihepatectomy for living donor liver transplantation

医学 外科 活体肝移植 肝移植 并发症 队列 回顾性队列研究 移植 内科学
作者
Chan Woo Cho,Gyu-Seong Choi,Do Hyeon Lee,Hyoung Joo Kim,Sung Su Yun,Dong-Shik Lee,Jinsoo Rhu,Jong Man Kim,Jae-Won Joh,Kyeong Sik Kim
出处
期刊:Liver Transplantation [Lippincott Williams & Wilkins]
卷期号:Publish Ahead of Print
标识
DOI:10.1097/lvt.0000000000000181
摘要

Right posterior section (RPS) graft for living donor liver transplantation (LDLT) is an alternative graft in a live liver donor with insufficient remnant left lobe (LL) volume and portal vein anomaly. Although there have been some reports regarding pure laparoscopic donor right posterior sectionectomy (PLDRPS), no study has compared PLDRPS versus pure laparoscopic donor right hemihepatectomy (PLDRH). The aim of our study was to compare the surgical outcomes of PLDRPS vs. PLDRH at centers achieving complete transition from open to laparoscopic approach in liver donor surgery. From March 2019 to March 2022, a total of 351 LDLTs, including 16 and 335 donors who underwent PLDRPS and PLDRH, respectively, were included in the study. In the donor cohort, there was no significant differences in major complication ( ≥ grade III) rate and comprehensive complication index (CCI) between the PLDRPS versus PLDRH group (6.3% vs. 4.8%; p = 0.556 and 2.7 ± 8.6 vs.1.7 ± 6.4; p = 0.553). In the recipient cohort, there was a significant difference in major complication ( ≥ grade III) rate (62.5% vs. 35.2%; p = 0.034), but no significant difference in CCI (18.3 ± 14.9 vs. 15.2 ± 24.9; p = 0.623) between the PLDRPS and PLDRH groups. PLDRPS in live liver donors with portal vein anomaly and insufficient LL was technically feasible and safe with experienced surgeons. The PLDRPS group might be comparable with the PLDRH group based on the surgical outcomes of donors and recipients. However, in terms of recipient outcomes, more careful selection of donor of the RPS graft and further research in a large number of cases are necessary to evaluate the usefulness of PLDRPS.
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