清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

The Effect of Bone Morphogenetic Protein-2 (BMP-2) on Volumetric and Histometric Outcomes for Peri-Implant Defects in the Animal Model: A Systematic Review and Meta-Analysis

荟萃分析 置信区间 医学 佩里 植入 牙科 骨形态发生蛋白2 随机对照试验 外科 内科学 生物 生物化学 体外
作者
Eric Lee,Alyssa Moy,Trung Vu Nguyen,Richard T. Kao,Guo‐Hao Lin
出处
期刊:International Journal of Oral & Maxillofacial Implants [Quintessence Publishing Company]
卷期号:38 (4): 651-666
标识
DOI:10.11607/jomi.10027
摘要

Purpose: To study the effect of BMP-2 on the volumetric and histometric changes in peri-implant defect treatments in animal models. Materials and Methods: An electronic search of four databases and a manual search of peer-reviewed journals for relevant articles were performed. Animal studies with data that compared the volumetric and/or histometric outcomes of peri-implant defect treatment with and without the use of BMP-2 were included. Meta-analyses were performed to analyze the weighted mean difference (WMD) and confidence interval (CI) for the recorded variables. Results: After completing the search process, 21 randomized controlled trials were included. The results of the meta-analyses showed that the WMD of bone-to-implant contact (%BIC) with 4 to 8 weeks and 12 to 24 weeks of follow-up was 15.50% (95% CI = 3.28% to 27.72%, P = .01) and 16.17% (95% CI = 11.17% to 21.16%, P < .00001), respectively, favoring the BMP-2 group. The WMD for the percentage of defect fill with 4 to 8 weeks and 12 to 24 weeks of follow-up was 15.88% (95% CI = 3.90% to 27.86%, P = .009) and 10.48% (95% CI = 0.95% to 20.02%, P = .03), respectively, favoring the BMP-2 group. The WMD for the vertical bone gain with 8 to 16 weeks of follow-up was 1.63 mm (95% CI = 0.58 to 2.67 mm, P = .002), also favoring the BMP-2 group. Conclusion: This review demonstrated that the use of BMP-2 in treating peri-implant defects showed better clinical and histometric outcomes than defects not treated with BMP-2 in animal models.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Dr.Tang完成签到 ,获得积分10
8秒前
17秒前
Siren发布了新的文献求助30
21秒前
披着羊皮的狼完成签到 ,获得积分10
55秒前
56秒前
sci完成签到 ,获得积分10
58秒前
1分钟前
酷波er应助科研通管家采纳,获得10
1分钟前
Ava应助科研通管家采纳,获得10
1分钟前
yindi1991完成签到 ,获得积分10
1分钟前
1分钟前
科研通AI5应助Siren采纳,获得10
1分钟前
1分钟前
Siren发布了新的文献求助10
1分钟前
ding应助瑁柏采纳,获得10
1分钟前
瑁柏完成签到,获得积分10
1分钟前
1分钟前
1分钟前
瑁柏发布了新的文献求助10
1分钟前
Siren发布了新的文献求助10
2分钟前
2分钟前
Ggap1发布了新的文献求助10
2分钟前
Ggap1完成签到,获得积分10
3分钟前
思源应助Siren采纳,获得10
3分钟前
Raul完成签到 ,获得积分10
3分钟前
Akim应助科研通管家采纳,获得10
3分钟前
Hello应助科研通管家采纳,获得10
3分钟前
3分钟前
3分钟前
Siren发布了新的文献求助10
3分钟前
Xu完成签到,获得积分20
3分钟前
荣浩宇完成签到 ,获得积分10
3分钟前
3分钟前
科研通AI5应助和谐乌龟采纳,获得10
4分钟前
4分钟前
4分钟前
mo发布了新的文献求助10
4分钟前
4分钟前
雪山飞龙完成签到,获得积分10
4分钟前
4分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968504
求助须知:如何正确求助?哪些是违规求助? 3513331
关于积分的说明 11167297
捐赠科研通 3248697
什么是DOI,文献DOI怎么找? 1794417
邀请新用户注册赠送积分活动 875030
科研通“疑难数据库(出版商)”最低求助积分说明 804664