再生(生物学)
表观遗传学
生物
计算生物学
神经科学
细胞生物学
遗传学
基因
作者
Xuemei Liu,Kehui Zhu,Jun Xiao
出处
期刊:aBIOTECH
[Springer Nature]
日期:2023-01-16
卷期号:4 (1): 31-46
被引量:13
标识
DOI:10.1007/s42994-022-00093-2
摘要
Abstract Ever since the concept of “plant cell totipotency” was first proposed in the early twentieth century, plant regeneration has been a major focus of study. Regeneration-mediated organogenesis and genetic transformation are important topics in both basic research and modern agriculture. Recent studies in the model plant Arabidopsis thaliana and other species have expanded our understanding of the molecular regulation of plant regeneration. The hierarchy of transcriptional regulation driven by phytohormone signaling during regeneration is associated with changes in chromatin dynamics and DNA methylation. Here, we summarize how various aspects of epigenetic regulation, including histone modifications and variants, chromatin accessibility dynamics, DNA methylation, and microRNAs, modulate plant regeneration. As the mechanisms of epigenetic regulation are conserved in many plants, research in this field has potential applications in boosting crop breeding, especially if coupled with emerging single-cell omics technologies.
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