化学
荧光
钙通道
钙
生物物理学
频道（广播）
L型钙通道
N型钙通道
组合化学
T型钙通道
有机化学
光学
电信
物理
计算机科学
生物
作者
Carlotta Borgarelli,Yvonne E. Klingl,Abril Escamilla‐Ayala,Catalina Scarponi,Rita La Rovere,Katarina Stoklund Dittlau,Geert Bultynck,Maurilio Sampaolesi,Matthias Schoenberger,Sebastian Munck,Ludo Van Den Bosch,Wim M. De Borggraeve,Ermal Ismalaj
标识
DOI：10.1021/acs.jmedchem.4c00565
摘要
Upregulation of L-type calcium channels (LTCCs) is implicated in a range of cardiovascular and neurological disorders. Therefore, the development of toolboxes that unlock fast imaging protocols in live cells is coveted. Herein, we report a library of first-in-class far-red small-molecule-based fluorescent ligands (FluoDiPines), able to target LTCCs. All fluorescent ligands were evaluated in whole-cell patch-clamp and live-cell Ca
科研通智能强力驱动
Strongly Powered by AbleSci AI
爱静静
加菲丰丰
shinysparrow
寻道图强
可口可乐了
乐乐乐乐乐乐
景辣条
充电宝
精明元霜
mmyhn
sirius
AireenBeryl531
星辰大海
kento
morena
丘比特
浅尝离白
Singularity
从容芮
领导范儿
皖公网安备34019202002308
