Enhancing fluid signal in driven‐equilibrium short‐TI inversion‐recovery imaging with short TR times: A feasibility study

Abstract Purpose Fluid‐sensitive turbo spin echo (TSE) MRI with short‐TI inversion‐recovery preparation for fat suppression (STIR) plays a critical role in the diagnostics of the musculoskeletal system (e.g., close to metal implants). Potential advantages of 3D acquisitions, however, are difficult to exploit due to long acquisition times. Shortening the TR incurs a signal loss, and a driven‐equilibrium (DE) extension reduces fluid signal even further. Methods The phase of the flip‐back pulse was changed by 180° relative to the conventional implementation (i.e., 90° along the positive x‐axis (90° x ) instead of −90° x ). After signal modeling and numerical simulations, the modification was implemented in STIR‐TSE sequences and tested on a clinical 3T system. Imaging was performed in the lumbar spine, and long‐TR images without DE were acquired as reference. CSF SNR and fluid‐muscle contrast were measured and compared between the sequences. Imaging was repeated in a metal implant phantom. Results A shortening of TR by 43%–57% reduced the CSF SNR by 39%–59%. A conventional DE module further reduced SNR to 26%–40%, whereas the modified DE recovered SNR to 59%–108% compared with the long‐TR acquisitions. Fluid‐tissue contrast was increased by about 340% with the modified DE module compared with the conventional extension. Similar results were obtained in implant measurements. Conclusions The proposed DE element for TSE‐STIR sequences has the potential to accelerate the acquisition of fluid‐sensitive images. DE‐STIR may work most efficiently for 3D acquisitions, in which no temporo‐spatial interleaving of inversion and imaging pulses is possible.