亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Nighttime Bracing or Exercise in Moderate-Grade Adolescent Idiopathic Scoliosis

医学 柯布角 脊柱侧凸 支撑 物理疗法 随机对照试验 撑杆 心理干预 特发性脊柱侧凸 保守治疗 儿科 外科 工程类 机械工程 精神科
作者
Anastasios Charalampidis,Elias Diarbakerli,Marlene Dufvenberg,Kourosh Jalalpour,Acke Ohlin,Anna Aspberg Ahl,Hans Möller,Allan Abbott,Paul Gerdhem,Birgitta Öberg,Hans Tropp,Anna Grauers,Ylva Bodén,Mats Hoffsten,Per Näsman,Henrik Hedevik
出处
期刊:JAMA network open [American Medical Association]
卷期号:7 (1): e2352492-e2352492 被引量:4
标识
DOI:10.1001/jamanetworkopen.2023.52492
摘要

Importance Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. For patients who reject full-time bracing, the effects of alternative, conservative interventions are unknown. Objective To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activity alone (PA) in preventing Cobb angle progression in moderate-grade AIS. Design, Setting, and Participants The Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS) randomized clinical trial was conducted from January 10, 2013, through October 23, 2018, in 6 public hospitals across Sweden. Male and female children and adolescents aged 9 to 17 years with an AIS primary curve Cobb angle of 25° to 40°, apex T7 or caudal, and skeletal immaturity based on estimated remaining growth of at least 1 year were included in the study. Dates of analysis were from October 25, 2021, to January 28, 2023. Interventions Interventions included self-mediated physical activity in combination with either NB or SSE or PA (control). Patients with treatment failure were given the option to transition to a full-time brace until skeletal maturity. Main Outcomes and Measures The primary outcome was curve progression of 6° or less (treatment success) or curve progression of more than 6° (treatment failure) seen on 2 consecutive posteroanterior standing radiographs compared with the inclusion radiograph before skeletal maturity. A secondary outcome of curve progression was the number of patients undergoing surgery up until 2 years after the primary outcome. Results The CONTRAIS study included 135 patients (45 in each of the 3 groups) with a mean (SD) age of 12.7 (1.4) years; 111 (82%) were female. Treatment success was seen in 34 of 45 patients (76%) in the NB group and in 24 of 45 patients (53%) in the PA group (odds ratio [OR], 2.7; 95% CI, 1.1-6.6). The number needed to treat to prevent curve progression with NB was 4.5 (95% CI, 2.4-33.5). Treatment success occurred in 26 of 45 patients (58%) in the SSE group (OR for SE vs PA, 1.2; 95% CI, 0.5-2.8). Up to 2 years after the primary outcome time point, 9 patients in each of the 3 groups underwent surgery. Conclusions and Relevance In this randomized clinical trial, treatment with NB prevented curve progression of more than 6° to a significantly higher extent than did PA, while SSE did not; in addition, allowing transition to full-time bracing after treatment failure resulted in similar surgical frequencies independent of initial treatment. These results suggest that NB may be an effective alternative intervention in patients rejecting full-time bracing. Trial Registration ClinicalTrials.gov Identifier: NCT01761305
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
干净涵梅发布了新的文献求助10
2秒前
华仔应助anyilin采纳,获得10
2秒前
11秒前
anyilin发布了新的文献求助10
17秒前
从容芮完成签到,获得积分0
22秒前
26秒前
JamesPei应助青木香采纳,获得10
30秒前
anyilin完成签到,获得积分20
44秒前
Chen完成签到 ,获得积分10
48秒前
53秒前
1分钟前
1分钟前
科研通AI5应助晚晚采纳,获得10
1分钟前
jianghs发布了新的文献求助30
1分钟前
袁钰琳完成签到 ,获得积分10
1分钟前
1分钟前
1分钟前
晚晚完成签到,获得积分10
1分钟前
晚晚发布了新的文献求助10
1分钟前
1分钟前
僦是卜够完成签到 ,获得积分10
2分钟前
徐悦月关注了科研通微信公众号
2分钟前
2分钟前
2分钟前
徐悦月发布了新的文献求助10
2分钟前
王志鹏发布了新的文献求助10
2分钟前
2分钟前
青木香发布了新的文献求助10
2分钟前
怡然的绮烟完成签到 ,获得积分10
2分钟前
青木香完成签到,获得积分10
2分钟前
Hello应助怡然的绮烟采纳,获得10
3分钟前
3分钟前
nolan完成签到 ,获得积分10
3分钟前
小蘑菇应助科研通管家采纳,获得10
3分钟前
kk完成签到 ,获得积分10
3分钟前
3分钟前
Elvira完成签到,获得积分10
3分钟前
先玩了玉发布了新的文献求助10
3分钟前
笨笨完成签到,获得积分10
4分钟前
vchen0621完成签到,获得积分0
4分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990031
求助须知:如何正确求助?哪些是违规求助? 3532108
关于积分的说明 11256334
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805146
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228