孟德尔随机化
骨矿物
高强度
医学
内科学
遗传学
生物
骨质疏松症
磁共振成像
遗传变异
放射科
基因
基因型
作者
Xiaoling Li,Xiaoju Wu,Guo-qiu Zhou,Dong-can Mo,Xiaozuo Lin,Pingkai Wang,Yinan Zeng,Man Luo
出处
期刊:Bone
[Elsevier]
日期:2024-06-22
卷期号:187: 117138-117138
标识
DOI:10.1016/j.bone.2024.117138
摘要
Greater white matter hyperintensities (WMH) in older adults have been associated with reduced bone mineral density (BMD) and increased fractures and falls. However, it is unclear whether there is a causal relationship between BMD reduction and WMH. In this study, Mendelian randomization (MR) was used to find the causality between WMH and estimated BMD (eBMD).
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