Decreased complexity of glucose time series index associated with adverse pregnancy outcomes in gestational diabetes mellitus

医学 妊娠期糖尿病 优势比 置信区间 怀孕 产科 胎龄 逻辑回归 混淆 糖尿病 内科学 妊娠期 内分泌学 遗传学 生物
作者
Guiling Liang,Mengyu Lai,Yaxin Wang,Na Li,Mei Kang,Jingyi Lu,Yanmei Su,Fang Fang,Yongde Peng,Xianming Xu,Jianrong Weng,Jian Zhou,Yufan Wang
出处
期刊:Diabetes, Obesity and Metabolism [Wiley]
卷期号:26 (9): 3587-3596 被引量:1
标识
DOI:10.1111/dom.15698
摘要

Abstract Aim We investigated the relationship between the complexity of the glucose time series index (CGI) during pregnancy and adverse pregnancy outcomes in women with gestational diabetes mellitus (GDM). Materials and Methods In this retrospective cohort study, 388 singleton pregnant women with GDM underwent continuous glucose monitoring (CGM) at a median of 26.86 gestational weeks. CGI was calculated using refined composite multiscale entropy based on CGM data. The participants were categorized into tertiles according to their baseline CGI (CGI <2.32, 2.32‐3.10, ≥3.10). Logistic regression was used to assess the association between CGI and composite adverse outcomes or large for gestational age (LGA). The discrimination performance of CGI was estimated using receiver operating characteristic analysis. Results Of the 388 participants, 71 (18.3%) had LGA infants and 63 (16.2%) had composite adverse outcomes. After adjustments were made for confounders, compared with those with a high CGI (CGI ≥3.10), participants with a low CGI (CGI <2.32) had a higher risk of composite adverse outcomes (odds ratio: 12.10, 95% confidence interval: 4.41‐33.18) and LGA (odds ratio: 12.68, 95% confidence interval: 4.04‐39.75). According to the receiver operating characteristic analysis, CGI was significantly better than glycated haemoglobin and conventional CGM indicators for the prediction of adverse pregnancy outcomes (all p < .05). Conclusion A lower CGI during pregnancy was associated with composite adverse outcomes and LGA. CGI, a novel glucose homeostasis predictor, seems to be superior to conventional glucose indicators for the prediction of adverse pregnancy outcomes in women with GDM.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
woshiwuziq完成签到 ,获得积分10
1秒前
drtianyunhong完成签到,获得积分10
1秒前
八八九九九1完成签到,获得积分10
5秒前
优雅的千雁完成签到,获得积分10
6秒前
没用的三轮完成签到,获得积分10
7秒前
9秒前
你我的共同完成签到 ,获得积分10
11秒前
mayberichard完成签到,获得积分10
13秒前
风信子deon01完成签到,获得积分10
16秒前
Pt-SACs发布了新的文献求助10
16秒前
香山叶正红完成签到 ,获得积分10
17秒前
wsg完成签到,获得积分10
17秒前
serendipity完成签到 ,获得积分10
19秒前
爆米花应助Yong-AI-BUPT采纳,获得10
20秒前
Pt-SACs完成签到,获得积分10
25秒前
刚子完成签到 ,获得积分10
26秒前
nicky完成签到 ,获得积分10
26秒前
果冻橙完成签到,获得积分10
28秒前
28秒前
田様应助科研通管家采纳,获得10
28秒前
Xiaoxiao应助科研通管家采纳,获得10
28秒前
思源应助科研通管家采纳,获得10
28秒前
29秒前
31秒前
火星人完成签到 ,获得积分10
32秒前
四叶草完成签到 ,获得积分10
33秒前
干净的沛蓝完成签到,获得积分10
33秒前
Yong-AI-BUPT发布了新的文献求助10
35秒前
琥1发布了新的文献求助10
35秒前
livra1058完成签到,获得积分10
35秒前
朴素的紫安完成签到 ,获得积分10
35秒前
火星上小土豆完成签到 ,获得积分10
36秒前
Silole完成签到,获得积分10
37秒前
Yong-AI-BUPT完成签到,获得积分10
44秒前
júpiter完成签到,获得积分10
45秒前
qiaoxi完成签到,获得积分10
45秒前
45秒前
cuddly完成签到 ,获得积分10
46秒前
mzrrong完成签到 ,获得积分10
47秒前
酢浆草小熊完成签到 ,获得积分10
48秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968578
求助须知:如何正确求助?哪些是违规求助? 3513391
关于积分的说明 11167428
捐赠科研通 3248822
什么是DOI,文献DOI怎么找? 1794499
邀请新用户注册赠送积分活动 875116
科研通“疑难数据库(出版商)”最低求助积分说明 804664