蛋白质亚单位
昆虫
生物
受体
气味
埃及伊蚊
冈比亚按蚊
生物物理学
离子通道
嗅觉
细胞生物学
化学
生物化学
植物
生态学
神经科学
免疫学
幼虫
疟疾
基因
作者
Jiawei Zhao,Andy Quaen Chen,Jae-Wook Ryu,Josefina del Mármol
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2024-06-13
卷期号:384 (6703): 1460-1467
被引量:5
标识
DOI:10.1126/science.adn6384
摘要
Most insects, including human-targeting mosquitoes, detect odors through odorant-activated ion channel complexes consisting of a divergent odorant-binding subunit (OR) and a conserved co-receptor subunit (Orco). As a basis for understanding how odorants activate these heteromeric receptors, we report here cryo-electron microscopy structures of two different heteromeric odorant receptor complexes containing ORs from disease-vector mosquitos
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