Superhydrophilic nanocomposite adsorbents modified via nitrogen-rich phosphonate-functionalized ionic liquid linkers: enhanced phosphopeptide enrichment and phosphoproteome analysis of tau phosphorylation in the hippocampal lysate of Alzheimer's transgenic mice

The superhydrophilic nanocomposite G@mSiO 2 @PEI-PFIL-Ti 4+ can be use as a platform to enrich phosphopeptides in ultralow abundance from real complicated bio-samples for a phosphoproteomic study.