Different effects of Bacillus coagulans vegetative cells and spore isolates on constipation-induced gut microbiota dysbiosis in mice

B. coagulans spore had higher survival rate in simulated GI environment than the corresponding vegetative cells. B. coagulans GBI-30 6086 and B. coagulans 90 spores relieve constipation by modulating the microbiota significantly associated with SCFA.