上睑下垂
小RNA
医学
癌症研究
长非编码RNA
竞争性内源性RNA
非编码RNA
自噬
程序性细胞死亡
癌症
计算生物学
生物
基因
核糖核酸
生物信息学
细胞凋亡
遗传学
作者
Dan Zhao,Tangwei Wu,Zheqiong Tan,Jia Xu,Zhongxin Lu
标识
DOI:10.1080/14737140.2024.2341737
摘要
Introduction Non-coding RNAs (ncRNAs), which are incapable of encoding proteins, are involved in the progression of numerous tumors by altering transcriptional and post-transcriptional processing. Recent studies have revealed prominent features of ncRNAs in pyroptosis, a type of non-apoptotic programmed cellular destruction linked to an inflammatory reaction. Drug resistance has arisen gradually as a result of anti-apoptotic proteins, therefore strategies based on pyroptotic cell death have attracted increasing attention. We have observed that ncRNAs may exert significant influence on cancer therapy, chemotherapy, radio- therapy, targeted therapy and immunotherapy, by regulating pyroptosis.
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